Are you waiting for stem cells or something to improve hearing?

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kokonut said:
I have to disagree with that one. For many, it is an improvement in one's quality of life. Go ask late deafened adults about their new found hearing with their CI.

I can probably relate to those who had CI for long time while as children grown into adulthood or those who were late deafened and got their CI by comparing my experiences with my hearing aid I use. Without it I am unable to enjoy my radio shows, my ragtime playing piano, use the phone with anybody, able to interact, involve and coordinate with my co-workers whether it's one to one, at a meeting or over a video conference meeting and much, much more.

Quality of life is rather subjective and personal so it's different for each person but with these amazing technological advances, yes, it does and can help improve a person's quality of life when one realizes what they have missed and the things it can do for you. Simply put.
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So, someone who would rate their quality of life as high without a CI just doesn't know what they are missing?:laugh2: Wow!:shock:
 
SkullChick said:
Lucia, what's PABI?
Hear again, ignore them, I have no interest into getting stem cell either and I had moderate loss and I don't miss it at all and ci sound better than aided at moderate loss.

CI doesn't improve quality of life it simply provide sound that hearing aid can't provide to have option of hearing when we want to, its just bonus and it doesn't affect one's quality of life if we don't have CI
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Exactly. And those that are always looking to something or someone to improve their quality of life for them will always come up short.
 
jillio said:
No, stem cell is made possible by using stem cells. It does not change the genetic make-up of the individual. And the stem cells used are not your stem cells, but stem cells donated by someone else.
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I've never said it will change the genetic make-up of the individual. This is not a cybernetic implant. This is not an external electronic device. This is a LIVING tissue..... hence - a genetic-level solution.
 
Jiro said:
I've never said it will change the genetic make-up of the individual. This is not a cybernetic implant. This is not an external electronic device. This is a LIVING tissue..... hence - a genetic-level solution.
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But that is just it, Jiro. It is not a genetic level solution. A genetic level solution would erradicate the gene responsible for deafness so that it is not passed on to future generations.
 
kokonut said:
Certainly. It'll also be a parental choice as well to treat/restore/cure their infants or children someday over a wide ranging number of conditions and ailments, including hearing loss which I'm sure would be a much more favorable route and choice than a cochlear implant.
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How exactly will stem cell therapy "cure" deafness? Deafness is not an illness, and therefore, is not something to be "cured". Likewise, since none of the long term effects or short term complication of stem cell therapy are known at this time, it cannot definatively be stated that it would be a more favorable route than CI. That remains to be seen, and cannot be determined for many years to come.
 
jillio said:
But that is just it, Jiro. It is not a genetic level solution. A genetic level solution would erradicate the gene responsible for deafness so that it is not passed on to future generations.
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no...... no......... no....... :facepalm:

tell me - how is this stem cell process done? it's in egg, fetus, etc. yes?
 
Jiro said:
here
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Read every post on the page you linked to. I do not see where HA said that CI improved the quality of her life. In fact, I saw several places where she said just the opposite. Perhaps I am missing something. Can you provide a specific quote?
 
jillio said:
Read every post on the page you linked to. I do not see where HA said that CI improved the quality of her life. In fact, I saw several places where she said just the opposite. Perhaps I am missing something. Can you provide a specific quote?
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yep you missed something. try again. :cool2:
 
Jiro said:
yep you missed something. try again. :cool2:
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I've read every post HA made on the page you linked to. There is no quote from her saying "CI improved my quality of life." Nor is there anything that implies it. Like I said, if you have something, you need to show it.
 
jillio said:
I've read every post HA made on the page you linked to. There is no quote from her saying "CI improved my quality of life." Nor is there anything that implies it. Like I said, if you have something, you need to show it.
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check HA's post history. Try Again. :cool2:
 
Jiro said:
check HA's post history. Try Again. :cool2:
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I checked the link you provided that would supposedly support your claim. It did not. It is not I that needs to try again.
 
jillio said:
I checked the link you provided that would supposedly support your claim. It did not. It is not I that needs to try again.
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oh well. if you say so..... :cool2:

like you said - 2 people understand it differently
 
jillio said:
Do you even read the research you attempt to use to support your claims? The reason that they are not using adult cells that have been reverted to stem cells is because the process is so variable and risky. They have discovered, through research, that while it is possible in some instances to revert an adult cell to stem cell status, it is not largely successful, nor do the reverted stem cells behave in the way that an actual stem cell does.

This is from your link:

Adult stem cells:

Adult stem cells are the back-up supply of cells extracted from adult tissue and organs that “auto- repair” when damaged. For example there are reparative cells in the skin and liver from which skin stem cells and liver stem cells can be extracted. Adult stem cells are multipotent, meaning that they are semi-programmed. For example, a skin stem cell cannot be transformed into a heart muscle cell. Adult skin stem cells can only become cells of the skin.

This clearly points out the flaw in your logic. If one does not have the stem cells necessary to regenerate cillia in the cochlea, then one cannot use one's own adult stem cells. If the adult stem cells needed for regeneration were available to the individual, those cells would repair the damage naturally. Therefore, donor stem cells are necessary. You cannot take an adult stem cell from another area of the body, and get it to regenerate tissue that it is not specialized for. Fetal stem cells, however, are not specialized, and can therefore be used for any kind of tissue. And they must be donated.
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Before you open you mouth again, adult stem cells are not just a few or limited but found in various areas in the human body....hence, the list of successful treatments of various conditions using adult stem cells. Unless you are denying that these things never happened? As a clarification when I say "adult stem cells" are the cells that come from your own body which is the safest and best bet to treatment a variety of conditions in a person's body.

Watch and listen to this video at the bottom of the webpage.
ASCTA


Let me ask you, how many places where adult stem cells are found in our own human body that has the potential ability to specifically regenerate a certain region in the body for a particular function? Are you saying that there are no "ear" adult stem cells? Here, let me help YOU for a change.

Finding ways to cure deafness and balance problems would represent a major scientific and clinical breakthrough. Recently, stem cells from the inner ear of adult mice have been identified. These adult stem cells are found in the utricle of the vestibular region of the inner ear. They have the characteristic features of stem cells in that they have the capacity for self renewal and expansion (they divide and multiply). They form spheres, which begin to differentiate into new cell types termed progenitor cells.

Some progenitor cells differentiate into cells that express proteins and genes present in the developing inner ear and nervous system. Under appropriate conditions, some cells differentiate into cells resembling hair cells, which have stereocilia hair bundles protruding from their surface and express specific hair cell marker proteins. The discovery of such cells is a first step towards the promise of restoring hearing and balance function.

What is the potential for stem cells? From a scientific perspective, scientists will first need to identify compounds and conditions that can increase the growth of stem cells and promote their differentiation into hair cells or supporting cells. From a clinical perspective, surgical and technical procedures need to be developed to successfully transplant stem cells into the inner ear. The critical question to be answered is whether transplanted stem cells can migrate into the correct location, differentiate into hair cells and restore hearing or balance.
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ISSCR :: Public : Beyond the Basics : Stem Cells and the Inner Ear

The concept is this. What's found in a mammalian mouse is a model of what's available or can be found in the human body.

What about stem cells for the eye? The liver? etc..etc..? Does not exist? Or what?

Adult stem cells are much further along in their research and have shown higher treatment successes.
http://www.stemcelldocs.org/uploads/Adult_vs.Embryonic.pdf
Adult Stem Cell Research

So, please, knock off with this "flaw in your logic" crapola the next time. The adult stem cell field is vast and new discoveries on what a human cell can do continues to grow. And that continues to be the good news.
 
kokonut said:
How's the dancing, Jiro?
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Pluripotent stem cells from the adult mouse inner ear.

In mammals, the permanence of acquired hearing loss is mostly due to the incapacity of the cochlea to replace lost mechanoreceptor cells, or hair cells. In contrast, damaged vestibular organs can generate new hair cells, albeit in limited numbers. Here we show that the adult utricular sensory epithelium contains cells that display the characteristic features of stem cells. These inner ear stem cells have the capacity for self-renewal, and form spheres that express marker genes of the developing inner ear and the nervous system. Inner ear stem cells are pluripotent and can give rise to a variety of cell types in vitro and in vivo, including cells representative of ectodermal, endodermal and mesodermal lineages. Our observation that these stem cells are capable of differentiating into hair cell-like cells implies a possible use of such cells for the replacement of lost inner-ear sensory cells.
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Pluripotent stem cells from the adult mouse inner ...[Nat Med. 2003] - PubMed Result

:cool2:
 
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