Are you waiting for stem cells or something to improve hearing?

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kokonut said:
Hmmm, interesting.
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I guess you got my PM. I wanted to take it to PMs rather than debate it out in my thread. Got instant messenger? Id like to chat with you, kokonut. I stayed out when you guys started debating/arguing. Anyone who wants to debate/argue, please don't get my thread locked again. Take it to PMs! My thread was a survey who was waiting for stem cells, just post about yourself and your own opinions/reasons but don't talk about anyone else.

We all have our own reasons and I am not going to debate/argue about them in this thread. Those who want CIs, that's their choice. Those who want stem cells or a cure, again that's their choice. I respect other's choice and hope they respect mine. Ive already said why I want stem cells. I have more reasons to add which ill do later, too tired now.
 
I find it interesting that people generally assume that people with CIs will not be able to do regenerative hair cells. It would be ironic if CI users respond to regenerative hair cells better than those who waited since the auditory stem/portion of the CI user's brain generally understands sounds better than those without.
 
Daredevel7 said:
I find it interesting that people generally assume that people with CIs will not be able to do regenerative hair cells. It would be ironic if CI users respond to regenerative hair cells better than those who waited since the auditory stem/portion of the CI user's brain generally understands sounds better than those without.
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Unless hair cell regeneration comes up with a way of re-creating what has been lost by avoiding the auditory nerve, this will not be an option for anyone who is implanted.

If hair cell regeneration were capable of this, I'd pass only because I see no reason to have this treatment since I'm already able to hear very well with my CIs. Being able to hear an extra 10 or 20 dB isn't that important to me.
 
Hear Again said:
Unless hair cell regeneration comes up with a way of re-creating what has been lost by avoiding the auditory nerve, this will not be an option for anyone who is implanted.

If hair cell regeneration were capable of this, I'd pass only because I see no reason to have this treatment since I'm already able to hear very well with my CIs. Being able to hear an extra 10 or 20 dB isn't that important to me.
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with a stem cell solution - you certainly won't be getting a mere 10-20 db. Try a near-humanlike quality. This is a genetic level solution..... not implant. That's a giant leap. CI was a giant leap as well compared to HA.
 
Jiro said:
with a stem cell solution - you certainly won't be getting a mere 10-20 db. Try a near-humanlike quality. This is a genetic level solution..... not implant. That's a giant leap. CI was a giant leap as well compared to HA.
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Actually, stem cell does not alter genetics. A person receiving stem cell that is deaf from a genetic cause will still carry the defective gene, and still be able to transmit that genetic deafness to offspring. And, it is an implant of sorts, as the stem cells will have to be implanted in the recipient in order to generate the hair cells. It, like anything else, is a treatment after the fact, not a cure or a way to erradicate deafness. Deafness will still occur.
 
jillio said:
Actually, stem cell does not alter genetics. A person receiving stem cell that is deaf from a genetic cause will still carry the defective gene, and still be able to transmit that genetic deafness to offspring. And, it is an implant of sorts, as the stem cells will have to be implanted in the recipient in order to generate the hair cells. It, like anything else, is a treatment after the fact, not a cure or a way to erradicate deafness. Deafness will still occur.
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Stem Cell is made possible by using your genes.... hence genetic level. and yes it's a treatment like CI. It is not a cure. Altering genetics? that's even way further in the future than stem cell research. Our genetic engineering is still at budding.

Thanks for clearing it up. My post could be misunderstood.
 
Jiro said:
with a stem cell solution - you certainly won't be getting a mere 10-20 db. Try a near-humanlike quality. This is a genetic level solution..... not implant. That's a giant leap. CI was a giant leap as well compared to HA.
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I don't care Jiro. I love the way I hear now with CIs, so I have no desire for stem cell treatment.
 
Jiro said:
Stem Cell is made possible by using your genes.... hence genetic level. and yes it's a treatment like CI. It is not a cure. Altering genetics? that's even way further in the future than stem cell research. Our genetic engineering is still at budding.

Thanks for clearing it up. My post could be misunderstood.
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No, stem cell is made possible by using stem cells. It does not change the genetic make-up of the individual. And the stem cells used are not your stem cells, but stem cells donated by someone else.
 
jillio said:
Actually, stem cell does not alter genetics. A person receiving stem cell that is deaf from a genetic cause will still carry the defective gene, and still be able to transmit that genetic deafness to offspring. And, it is an implant of sorts, as the stem cells will have to be implanted in the recipient in order to generate the hair cells. It, like anything else, is a treatment after the fact, not a cure or a way to erradicate deafness. Deafness will still occur.
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Exactly. This is what I pointed out in an earlier post.
 
jillio said:
No, stem cell is made possible by using stem cells. It does not change the genetic make-up of the individual. And the stem cells used are not your stem cells, but stem cells donated by someone else.
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Not necessarily true.
 
Until they are able to successfully harvest adult cells and return them to a stem cell without failure and with the ability to perform exactly as a stem cell does, it is true.
 
deafdude1 said:
That's the beauty of it, you don't have to ask for near normal hearing, you can have fewer hair cells regenerated and go from say 90db HL down to perhaps 60db HL. Youd still experience silence since a quiet room is 30db and a noisy room is usually less than 60db. But aided, youd hear excellent with only a 60db moderate loss.

Besides, ive said in my first post that stem cells won't restore normal hearing for a long while, it will first start out with people experiencing around 20db improvement in their hearing then as the technology matures, the improvements will gradually increase. I would take normal hearing but that's the icing on the cake. I only need the first 20db improvement in my hearing to hear 100% with HAs. Any further improvement will simply let me hear more unaided and be less dependant on HAs which is still a good thing, it's the icing on the cake.





Exactly. 20 years ago, it was all talk. Now it's starting to get serious. I bet in 5 years, we will see it being done on apes, cats, dogs and in 10 years, on humans.
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I grew up with moderate HL of 50 db for first 17 years of my life and even with that, my CI sound so much better and more clarity to it than hearing aid aided at 50 db hearing loss. So for stem cell, hell no do you really want hearing that you won't be able to turn it off? What if the stem cell only can go to normal hearing level not up to 50 like you wanted you can't turn it off, for most it'll makes people have serious psychological problem or trauma from not being able to turn it off
 
Er, there were successes on using patients' own stem cells to literally "heal" themselves.

First-Ever Procedure Uses Patient's Own Adult Stem Cells to Treat Stroke Effects

And this one...

In Barcelona on June 2008, doctors implanted a newly constructed windpipe into a 30 year old patient. The windpipe was partially constructed with tissue grown from the patient’s own adult stem cells. This is one of the first transplants in which the doctors created a functional, biological structure that can't be rejected. This advancement eliminates the need for anti-rejection drugs, which can often be accompanied by side effects such as high blood pressure, cancer and kidney failure. Details of the Clinical transplantation of a tissue-engineered airway can be found online in The Lancet medical journal.
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What are stem cells? Adult, Fetal & Cord Blood Stem Cells


Secondly, the use of one's own adult stem cells reduces dramaticallly any tissue cell rejection.

Adult stem cells have used successfully to treat a variety of conditions.
Cancers:

Brain Cancer
Retinoblastoma
Ovarian Cancer
Skin Cancer: Merkel Cell Carcinoma
Testicular Cancer
Tumors abdominal organs Lymphoma
Non-Hodgkin’s lymphoma
Hodgkin’s Lymphoma
Acute Lymphoblastic Leukemia
Acute Myelogenous Leukemia
Chronic Myelogenous Leukemia
Juvenile Myelomonocytic Leukemia
Chronic Myelomonocytic Leukemia
Cancer of the lymph nodes: Angioimmunoblastic Lymphadenopathy
Multiple Myeloma
Myelodysplasia
Breast Cancer
Neuroblastoma
Renal Cell Carcinoma
Various Solid Tumors
Soft Tissue Sarcoma
Ewing’s Sarcoma
Waldenstrom’s macroglobulinemia
Hemophagocytic lymphohistiocytosis
POEMS syndrome
Myelofibrosis
Auto-Immune Diseases

Diabetes Type I (Juvenile)
Systemic Lupus
Sjogren’s Syndrome
Myasthenia
Autoimmune Cytopenia
Scleromyxedema
Scleroderma
Crohn’s Disease
Behcet’s Disease
Rheumatoid Arthritis
Juvenile Arthritis
Multiple Sclerosis
Polychondritis
Systemic Vasculitis
Alopecia Universalis
Buerger’s Disease
Cardiovascular

Acute Heart Damage
Chronic Coronary Artery Disease
Ocular

Corneal regeneration
Immunodeficiencies

Severe Combined Immunodeficiency Syndrome
X-linked Lymphoproliferative Syndrome
X-linked Hyper immunoglobulin M Syndrome
Neural Degenerative Diseases and Injuries

Parkinson’s Disease
Spinal Cord Injury
Stroke Damage
Anemias and Other Blood Conditions

Sickle Cell Anemia
Sideroblastic Anemia
Aplastic Anemia
Red Cell Aplasia
Amegakaryocytic Thrombocytopenia
Thalassemia
Primary Amyloidosis
Diamond Blackfan Anemia
Fanconi’s Anemia
Chronic Epstein-Barr Infection
Wounds and Injuries

Limb Gangrene
Surface Wound Healing
Jawbone Replacement
Skull Bone Repair
Other Metabolic Disorders

Hurler’s Syndrome
Osteogenesis Imperfecta
Krabbe Leukodystrophy
Osteopetrosis
Cerebral X-Linked Adrenoleukodystrophy
Liver Disease

Chronic Liver Failure
Liver Cirrhosis
Bladder Disease

End-Stage Bladder Disease
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http://www.stemcellresearch.org/facts/asc-refs.pdf

Adult stem cells harvested from one own's bone marrow is a common procedure to treat leukemia and other types of cancer, as well as various blood disorders.

Stem Cell Therapies Today

Using adult stem cells from another person, called an allograft, are always at risk of rejection by the recipient's immune system while from one's own do not face that rejection dilemma.

News:Adult Stem Cells Show Same Ability to Self-Renew as Embryonic Cells - Regenerative Medicine at the McGowan Institute
 
Lucia, what's PABI?
Hear again, ignore them, I have no interest into getting stem cell either and I had moderate loss and I don't miss it at all and ci sound better than aided at moderate loss.

CI doesn't improve quality of life it simply provide sound that hearing aid can't provide to have option of hearing when we want to, its just bonus and it doesn't affect one's quality of life if we don't have CI
 
deafdude1 said:
Those who want CIs, that's their choice. Those who want stem cells or a cure, again that's their choice.
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Certainly. It'll also be a parental choice as well to treat/restore/cure their infants or children someday over a wide ranging number of conditions and ailments, including hearing loss which I'm sure would be a much more favorable route and choice than a cochlear implant.
 
kokonut said:
Er, there were successes on using patients' own stem cells to literally "heal" themselves.

First-Ever Procedure Uses Patient's Own Adult Stem Cells to Treat Stroke Effects

And this one...


What are stem cells? Adult, Fetal & Cord Blood Stem Cells


Secondly, the use of one's own adult stem cells reduces dramaticallly any tissue cell rejection.

Adult stem cells have used successfully to treat a variety of conditions.


http://www.stemcellresearch.org/facts/asc-refs.pdf

Adult stem cells harvested from one own's bone marrow is a common procedure to treat leukemia and other types of cancer, as well as various blood disorders.

Stem Cell Therapies Today

Using adult stem cells from another person, called an allograft, are always at risk of rejection by the recipient's immune system while from one's own do not face that rejection dilemma.

News:Adult Stem Cells Show Same Ability to Self-Renew as Embryonic Cells - Regenerative Medicine at the McGowan Institute
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Do you even read the research you attempt to use to support your claims? The reason that they are not using adult cells that have been reverted to stem cells is because the process is so variable and risky. They have discovered, through research, that while it is possible in some instances to revert an adult cell to stem cell status, it is not largely successful, nor do the reverted stem cells behave in the way that an actual stem cell does.

This is from your link:

Adult stem cells:

Adult stem cells are the back-up supply of cells extracted from adult tissue and organs that “auto- repair” when damaged. For example there are reparative cells in the skin and liver from which skin stem cells and liver stem cells can be extracted. Adult stem cells are multipotent, meaning that they are semi-programmed. For example, a skin stem cell cannot be transformed into a heart muscle cell. Adult skin stem cells can only become cells of the skin.

This clearly points out the flaw in your logic. If one does not have the stem cells necessary to regenerate cillia in the cochlea, then one cannot use one's own adult stem cells. If the adult stem cells needed for regeneration were available to the individual, those cells would repair the damage naturally. Therefore, donor stem cells are necessary. You cannot take an adult stem cell from another area of the body, and get it to regenerate tissue that it is not specialized for. Fetal stem cells, however, are not specialized, and can therefore be used for any kind of tissue. And they must be donated.
 
SkullChick said:
Lucia, what's PABI?
Hear again, ignore them, I have no interest into getting stem cell either and I had moderate loss and I don't miss it at all and ci sound better than aided at moderate loss.

CI doesn't improve quality of life it simply provide sound that hearing aid can't provide to have option of hearing when we want to, its just bonus and it doesn't affect one's quality of life if we don't have CI
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but Hear Again just admitted that CI greatly improved her quality of life.
 
SkullChick said:
Lucia, what's PABI?
CI doesn't improve quality of life it simply provide sound that hearing aid can't provide to have option of hearing when we want to, its just bonus and it doesn't affect one's quality of life if we don't have CI
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I have to disagree with that one. For many, it is an improvement in one's quality of life. Go ask late deafened adults about their new found hearing with their CI.

I can probably relate to those who had CI for long time while as children grown into adulthood or those who were late deafened and got their CI by comparing my experiences with my hearing aid I use. Without it I am unable to enjoy my radio shows, my ragtime playing piano, use the phone with anybody, able to interact, involve and coordinate with my co-workers whether it's one to one, at a meeting or over a video conference meeting and much, much more.

Quality of life is rather subjective and personal so it's different for each person but with these amazing technological advances, yes, it does and can help improve a person's quality of life when one realizes what they have missed and the things it can do for you. Simply put.
 
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