faire_jour
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Wow, you missed the sarcasm in that, which is surprising since I laid it on soooo thick...
Stem cells heal hearing loss
- Thread starter stemcellblogger
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Wow, you missed the sarcasm in that, which is surprising since I laid it on soooo thick...
kokonut
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I laid it out just in case you didn't really know. Can never tell nowadays.
There's still alot of misinformation against stem cells. Adult and cord blood stem cells never cause tumors(you won't find a single case) they are safer than any surgery/medicine out there. The questions you guys ask have been answered in my blog(link in sig)
somedeafdudefromPNW
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"never caused tumours"
That's a big thing to say... considering that we haven't even begun using it much more than yesterday. (Relax, deafdude, don't go all scientific and exact on me... I meant "yesterday" in a literary sense in that it is still fairly recent.)
faire_jour
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YOU answered the questions in your blog, not a scientist or a doctor. Why on earth would we take that as evidence?
jillio
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Exactly. We don't have the longitudinal data available to make that determination.:roll:
kokonut
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DD, whenever there is a cell that can divide and replicate there is *always* a chance for it to become cancerous or give rise to tumors. Just that using our own adult stem cell reduce that risk of rejection versus embryonic. Regardless, adult stem cells have been proven to be more and more promising in the field of regenerative medicine.
Potential risk of tumor formation from adult stem cell therapy could be underestimated Hematopoiesis: Blood Stem Cell & Lineages
Stem cell treatment and tumor risk ? XCell-Center
Adult stem cells do not increase tumor risk
Scientists Use Adult Stem Cells to Fix Tumor Problems of Embryonic Stem Cells
Scientists Use Adult Stem Cells to Fix Tumor Problems of Embryonic Stem Cells
Discovery Institute - Bioethics - Articles/News - Stem Cell News That Isn't Fit For Print
EMBRYONIC STEM CELLS are another potential source for regenerative treatments. But, we pointed out, unlike adult stem cell treatments, ES cells cannot be used in human studies because of two fundamental safety issues. First, they cause tumors in animal studies. For example, in one recent experiment, ES cells were injected into a mouse in the hope they would rebuild the animal's damaged knee. Instead, the cells obliterated the knee by stimulating tumor growth. (More recently, an adult stem cell animal study successfully rebuilt joints without causing tumors.)
"Adult Stem Cells Saved My Life" - Blogger News Network
No human has been injected because of all the complications with embryonic stem cells, including cancer. In the meantime, adult stem cells, without carrying the ethical and moral baggage, continue to work successfully. And with new methods being discovered that make adult stem cells as flexible as embryonic, there is absolutely no need to even go down the embryonic path.
Discovery Institute - Bioethics - Articles/News - Umbilical Accord
And there is even more good news about umbilical cord blood stem cells: Unlike embryonic stem cells, UCB stem cells don't cause dangerous tumors. Moreover, they are easier to tissue-type to prevent rejection than are bone marrow stem cells. And here's another big plus: This research is utterly uncontroversial. No embryos are being cloned. No embryos are being destroyed.
Risk? There have been no cases of tumors from adult stem cells that I could find on Google. The risks are very low and far safer than any drug/surgery.
jillio
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Google isn't the best place to gather medical experimentation information. You need to go to the professional journals. Anytime you are using a .com site, you are getting biased information that is rarely accurate.
You can't find cases of tumors because (how many times do we have to say it?) the longitudinal data is not available. That certainly doesn't mean that it doesn't cause tumors. It means no one knows because not enough time has passed to determine longitudinal risk.:roll:
kokonut
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I didn't say increase risk of tumor. I said there is a reduced risk of *rejection* when compared with embryonic due to using stem cells that came from elsewhere and not from your own body. Again, any cell division and replication there is always a risk of cancer or tumor. Our own body continues daily cell division and replicating to replace skin, our lining inside the intestines where it sloughs of daily, other organs and so far. Over time it can give rise to cancer or produce tumors. Although I don't see it from adult stem cells point of view. Just more of the embryonic kind I see it as an increased risk of it happenng.
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I would not get stem cell treatment b/c although they say it "works" no one still knows the long term effects of stem cells.
Look at Dolly the Sheep - she aged rapidly; at age 5 she was showing the age of a 12 year old sheep. She had quite a few health issues from what I understood.
There's so much scientist still don't know and won't know for several decades, and due to those reasons, I choose not to seek stem cell treatment for my deafness.
Look at Dolly the Sheep - she aged rapidly; at age 5 she was showing the age of a 12 year old sheep. She had quite a few health issues from what I understood.
There's so much scientist still don't know and won't know for several decades, and due to those reasons, I choose not to seek stem cell treatment for my deafness.
kokonut
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That was not from adult stem cells.
Dolly's Creator Moves Away from Cloning and Embryonic Stem Cells: Scientific American
Adult stem cells are stem cells from your own body. So, virtually no worry about rejection.
What happens if you inject your own stem cell that already have damaged DNA?
Also, the risks may not be realized until years later. From what I read, it can take years for cancer cells to metastasize to other organs. For example, smoking can cause immediate damage to DNA but it doesn't metastasize until decades later which is why the risk of lung cancer remains higher than those who never smoked.
I can see how stem cell technology can cure some diseases, especially if it involves cell division and replace bad ones but I have a hard time believing it can regenerate dead nerves that's already been damaged for decades, notably for deafness and spinal cords. The only way I could see that can make nerves regenerate is to damage the nerves again to stimulate nerve regeneration. I don't believe that just giving an injection will regenerate damaged nerves.
While it may make sense to treat terminally ill with stem cell technology, I'd rather that they get the treatment first and see how it goes for another decade before anyone with non life threatening diseases or disorders get it.
Also, the risks may not be realized until years later. From what I read, it can take years for cancer cells to metastasize to other organs. For example, smoking can cause immediate damage to DNA but it doesn't metastasize until decades later which is why the risk of lung cancer remains higher than those who never smoked.
I can see how stem cell technology can cure some diseases, especially if it involves cell division and replace bad ones but I have a hard time believing it can regenerate dead nerves that's already been damaged for decades, notably for deafness and spinal cords. The only way I could see that can make nerves regenerate is to damage the nerves again to stimulate nerve regeneration. I don't believe that just giving an injection will regenerate damaged nerves.
While it may make sense to treat terminally ill with stem cell technology, I'd rather that they get the treatment first and see how it goes for another decade before anyone with non life threatening diseases or disorders get it.
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But wouldn't this be the same as taking your own stem cells, reverting them back to unspecialized stem cells then directing them to grow into a certain specialized cell and eventually into a body part that may be damaged or missing? Sure, your body would not reject them, but maybe it will as basically it's an extra set of code, so the RNA/DNA replicating mechanisms would attempt to suppress it.
Not only that, what if your body is just simply programmed in such that certain specialized cells are/will be malfunctioned/missing?
Like say for me, I am completely deaf in my L ear and HOH in my R ear. If I used my own stem cells to grow into ear cells, would the not be programmed to be d/hh cells as it is coded that L ear cells are deaf and my R ear cells are HH??
DNA/RNA is very complex and we still don't know everything about as it is still fairly new.
Not only that, what if your body is just simply programmed in such that certain specialized cells are/will be malfunctioned/missing?
Like say for me, I am completely deaf in my L ear and HOH in my R ear. If I used my own stem cells to grow into ear cells, would the not be programmed to be d/hh cells as it is coded that L ear cells are deaf and my R ear cells are HH??
DNA/RNA is very complex and we still don't know everything about as it is still fairly new.
jillio
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I see you are actually thinking about this in depth with the questions you have asked. I wish everyone would take such a realistic perspective and realize that thare are more unanswered questions than answered ones when it comes to stem cell research.