This policy is a revision of the policy posted on November 1, 1995.
CLINICAL REPORT
PEDIATRICS Vol. 110 No. 5 November 2002, pp. 1024-1027
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AMERICAN ACADEMY OF PEDIATRICS
Perinatal Care at the Threshold of Viability
Hugh MacDonald, MD and Committee on Fetus and Newborn
In the United States, an increase in the number of births of extremely preterm infants and in their survival potential has occurred over the last decade. Determining the survival prognosis for the infant of a pregnancy with threatened preterm delivery between 22 and 25 completed weeks of gestation remains problematic. Many physicians and families encounter the difficulty of making decisions regarding the institution and continuation of life support for an infant born within this threshold period. This report addresses the process of counseling, assisting, and supporting families faced with the dilemma of an extremely preterm delivery.
The survival rate for infants born preterm has improved over the last 2 decades and is likely to continue to improve. An infant born at the threshold of viability presents a variety of complex medical, social, and ethical decisions. Although the incidence of such births is low, the number of extremely preterm births has increased, and the impact on the infants, their families, the health care system, and society is profound.
The survival rate for infants born from 22 to 25 weeks of gestation increases with each additional week of gestation.1,2 However, the incidence of moderate or severe neurodevelopmental disability in surviving children assessed at the age of 18 to 30 months is high (approximately 30%–50%) and does not appear to decrease over the 23- to 25-week gestation period.2–9 Many of these infants require prolonged intensive and long-term care. The commitment for , multidisciplinary, lifelong, and costly. Because the families bear theall aspects of care may be extensive emotional and financial consequences of the birth of an extremely preterm infant, it is essential to inform the prospective parents regarding the expectations for infant survival and outcome and the risks and benefits of various approaches to care.