In one of Ray Bradbury's stories for The Martian Chronicles, humans were the martians. Fifty Books Project 2013: The Martian Chronicles by Ray Bradbury
So be sure to get there to have your input into MSL!
I think some of the early signs will be for Cold and Can't Breath. 
It might be a small language. There may also be a need to allow for decreased dexterity due to gloves of suits required when roaming outside.
