Any New updates On Stem cell research?

J

Jack-O-Lope

Guest
Or news about hair cell regeneration? Thoughts?? Discuss it.
 
hair cell, or ganglion cell regeneration is still FAR off into the future (30+ years) although the techniques and theory are getting better every year. I have been putting alot of study into these theories as well as more modern and understood practices (ABI's and CI's)

I have discussed this issue with a few very well versed doctors and they have said the same thing. We are still a very far way away from this being tested on human subjects. CI's and ABI (auditory brainstem implant) is still going to be the standard for allowing severe and profoundly deaf individuals to "regain hearing" in what ever form that may be.

not to get too far off topic.. but I have been doing some research on a technique a Dr. described during a CI procedure that has been shown online @ OR-Live: Live and On-Demand Medical Webcasts regarding injections of steroids into the cochlea after and a few weeks following implantation which as he suggested helps to limit ganglion cell damage after insertion of the electrode. I have yet to find any real information regarding this procedure. But, if this procedure becomes more mainstream it would allow for much greater flexibility in approving candidates who would otherwise be rejected due to loss in specific frequencies being "not ideal"

To go one step further on that.. Medel has come out with a really interesting concept in there new "hybrid" cochlear implant called Duet EAS. Which basically is a CI which has a special electrode that only activates high frequencies (above 1KHz) and uses a standard type hearing aid for frequencies below 1KHz.

Sorry again to get a bit off-topic.. but I am just discussing new technology and ideas going on in the world
 
I serve on UCI's Stem Cell PAC. Bone marrow blastocysts best choice for hair cell regeneration. A lot of these 'well versed' doctors are not part of stem cell research centers and they wont even mention were hardly 'far' from trying this on humans already. In fact we have servicemen from Iraq regaining their hearing as quickly as 45 days from treatment.

Richard Roehm
 
Richard,

I have a few questions for you,

What is the basic procedure for this?
What degrees of loss have you tried this treatment on? results?
Have any of these patients been non-military?
Has any testing been done on those who have had hearing loss for many years before undergoing this treatment?

I would be VERY interested in getting any information you have regarding the procedures you have used.

Actually I have alot of questions..but I think this will do for now.

Thanks!
 
I rejected the C I cause its not real hearing.They are just man made robotic sounds doesnt sound like the real thing the way its supposed to sound.
 
Jack-O-Lope said:
I rejected the C I cause its not real hearing.They are just man made robotic sounds doesnt sound like the real thing the way its supposed to sound.
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It depends a lot on your previous auditory experience. If you were once hearing, then the chances are you'll get good results with a CI that sounds pretty natural. A deaf adult with not much prior auditory experience is more likely to experience what you describe above and with headaches on top of that.

That will not change with hair cell regeneration technology because hearing isn't just about the ears but also about the brain. If you have missed the critical auditory system development period (usually first 3-5 years of life) you still won't hear like a hearing person with hair cell regeneration. You'll be able to "hear" sounds but your brain won't be able to process them very well.
 
I remember an article about the regeneration cells.

The FDA did not approve it. I am trying to remember what the article was all about. The research was not successful so far I know. They implanted some cells in a bird's cochlear to make the hair cells grow. In a week, they grow successfully. The problem is that the hairs were still growing so they put some chemicals to make them stop growing. All hair cells died. They have tried many different chemicals, and they have too many side effects. I heard that the fund was not enough for them to research it. They need 10 millions dollars for this project. Some wealthy people already gave them a few millions of dollars so the research was continued, I assumed, for 10 years. Then, the research is stopped, and they are still waiting for more funds. Now, I don't know what to believe because their money was spent to provide them for labs and equipments. Do they really need more money for one "small" research? Does it has to do with the law that banned stem cells in the United States?
 
Web... I read this same article but Nesmuth is talking about the use of human subjects for testing.. I find this very amazing giving the fact that just last year the latest testing involved mice embryos and birds..

As for the ban on stem cells.. This has to do with using human embryos to harvest blastocysts which are basically clumps of stem cells. The type of stem cells you are able to harvest from human embryos (Pluripotent) are what doctors and scientists are interested in most.. These Pluripotent cells have the ability to product any kind of cell that your body currently has.

What Nesmuth was referring to was using bone marrow cells to harvest blastocysts, but the problem with this is.. The cells they create tend to bond to the existing cells you are wanting to repair and do not reproduce. But if they are using it in human patients they must have found a way around this problem.. Hopefully Nesmuth can chime in with some of the latest info.
 
Jack-O-Lope said:
I rejected the C I cause its not real hearing.They are just man made robotic sounds doesnt sound like the real thing the way its supposed to sound.
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as the wise man once said - indeed. which is why i'm investing my time in researching hair cell regeneration [stem cells] or nanotechnology -- to repair the damaged cells or nerves at the cellular level.
 
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The posts I read here made me a little desperate about stem cell 'cure' :( it is sad to realize that science has a long way to 'repair' hair cells. I thought it would taken me ten or fifteen years for a stem cell repair .. In the current conditions , I should be more focused on CIs .. :hmm: thanks to cochlear implant manufacturers for 'supporting' our wishes about hearing again even though we know it is not natural hearing.
 
Well, I have a friend who went deaf a little over 5 years ago.. 3 years ago she was implanted with a CI (cochlear americas) .. I have been talking with her about sound differences.. she says all the sounds that she remembers (her husbands voice.. friends voices.. music..) sound much the same.. She has worked hard with her mapping to get it perfect for her though.. but I think that she is a postcard for CI success.

***
Nesmuth.. hopefully your still out there.. ! check your inbox!
 
webexplorer said:
I remember an article about the regeneration cells.

The FDA did not approve it. I am trying to remember what the article was all about. The research was not successful so far I know. They implanted some cells in a bird's cochlear to make the hair cells grow. In a week, they grow successfully. The problem is that the hairs were still growing so they put some chemicals to make them stop growing. All hair cells died. They have tried many different chemicals, and they have too many side effects. I heard that the fund was not enough for them to research it. They need 10 millions dollars for this project. Some wealthy people already gave them a few millions of dollars so the research was continued, I assumed, for 10 years. Then, the research is stopped, and they are still waiting for more funds. Now, I don't know what to believe because their money was spent to provide them for labs and equipments. Do they really need more money for one "small" research? Does it has to do with the law that banned stem cells in the United States?
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Thats why im voting for "Hillary Rodham Clinton" I had enough with the bush adminstration. George Bush vetoed the stem cell bill twice.The man doesnt care about anybody but himself:mad:
 
Thats why im voting for "Hillary Rodham Clinton" I had enough with the bush adminstration. George Bush vetoed the stem cell bill twice.The man doesnt care about anybody but himself
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Dubba, only vetoed them due to the ethical concerns with using human embryos for harvesting stem cells. There are other methods to harvesting stem cells though at the moment embryos are the most effective. Just because a democrat may or may not show up in the white house does not mean that they will not be pressured by the religious right to veto the same bill. But that is another discussion all together.
 
Jasper said:
Dubba, only vetoed them due to the ethical concerns with using human embryos for harvesting stem cells. There are other methods to harvesting stem cells though at the moment embryos are the most effective. Just because a democrat may or may not show up in the white house does not mean that they will not be pressured by the religious right to veto the same bill. But that is another discussion all together.
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I wish that it would be ready so that we all able to hear and able to get a normal job even promoted without a discrimination.
 
well web, it may not be that simple.. not to mention how long it will take to perfect such a technique.. there is the issue that pre-lingual deafened individuals have with CI.. that is the "atrophy" of the auditory nerve and hearing/speech center of the brain, depending on severity of hearing loss. Even if it were perfected, the main problem would be introducing sound to patients who have never experienced it before.. there would be great comprehension issues as well as "information overload". But, who knows.. hopefully I am wrong on this assumption.
 
Hello, I need let you know that Jack-O-Lope is buckdodgers/ravensteve, that use under multi-account.

Check his grammar so carefully.
 
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